San Antonio's housing stock reflects its age as one of Pasco County's oldest settlements, with an established core of historic and older single-family homes on small-town lots. Around this center, newer residential development has arrived on the city's edges, including master-planned communities that serve the wider north Tampa corridor. The market thus spans from preserved older homes in the historic grid to modern subdivisions nearby, offering a mix that suits both those seeking small-town character and those wanting newer construction with access to the Tampa region.

The heart of San Antonio is its historic core, organized around the Catholic church and the town's original 1880s colony layout, with older homes and quiet, tree-lined streets. This center preserves the community's founding-era character. Beyond it, the city transitions into newer subdivisions and the surrounding Pasco County countryside, where rolling hills and pastoral roads define the landscape. Nearby St. Leo, home to Saint Leo University and the abbey, functions as a close institutional neighbor, and Dade City anchors the broader east Pasco area.

San Antonio's lifestyle is defined by its small scale, its deep Catholic roots, and its hilly countryside. The town maintains a close community feel, with a historic core centered on the parish church that predates the arrival of the Benedictines at Saint Leo. Cyclists are a familiar sight on the surrounding country roads, drawn by terrain unusual for Florida, and residents enjoy a quiet pace while depending on nearby Dade City, Zephyrhills, and Wesley Chapel for broader shopping and services. The presence of Saint Leo University nearby also brings a steady, mild academic influence to the area.

Public education in San Antonio falls under Pasco County Schools, the district serving the wider county, with additional public, charter, and faith-based options in and around Dade City and San Antonio. Higher education is anchored by Saint Leo University, a Catholic liberal arts institution located in neighboring St. Leo, and Pasco-Hernando State College, which operates campuses within roughly a 20-minute drive. This combination gives San Antonio residents access to both local K-12 schooling and nearby college opportunities.

San Antonio sits in east-central Pasco County, north of Tampa, within commuting range of the Tampa Bay metropolitan area. The area is served by the region's interstate and state-highway corridors, placing Dade City, Zephyrhills, and Wesley Chapel a short drive away and connecting residents to jobs across the broader Tampa region. Daily needs are met locally or in neighboring towns, while the city itself retains a low-traffic, small-town road network suited to its hillside setting.

San Antonio's signature recreation is road cycling, with riders drawn to the area's rolling hills and quiet country roads on routes ranging from 50 to 100 miles or more. The surrounding Pasco countryside also supports walking and rural exploration, while nearby Dade City, Zephyrhills, and Wesley Chapel provide parks, sports facilities, and community events. The town's historic setting and its proximity to Saint Leo University's campus add further points of interest within a short drive.